Omeprazole | Drugs | BNF | NICE
Can increase the risk of fractures (particularly when used at high doses for over a year in the elderly); may increase the risk of gastro-intestinal infections (including Clostridioides difficile infection); may mask the symptoms of gastric cancer; may reduce absorption of vitamin B 12 with long-term treatment; patients at risk of osteoporosis. Cautions, further …